Biomedical research and clinical practice are struggling to cope with the growing complexity that the progress of health care involves. The most challenging diseases, those with the largest socio-economic impact (cardio-vascular conditions, musculoskeletal conditions, cancer, neuro-degenerative conditions, etc), are all characterized by a complex genotype–phenotype interaction and by a “systemic” nature that poses a challenge to the traditional reductionist approach.
The current knowledge about these diseases is fragmentary, as it is associated with molecular and cellular processes on the one hand and with tissue and organ phenotype changes (related to clinical symptoms of disease conditions) on the other. Thanks to the VPH technologies, this problem could be solved. The goal of in silico medicine research is to capture all these fragments of knowledge into predictive and personalised models that will make possible the investigation of the human body as a whole.

- Reference: Annu Rev Biomed Eng. 2016 Jul 11;18:103-23. doi: 10.1146/annurev-bioeng-110915-114742 “The Virtual Physiological Human: Ten Years After.” Viceconti M. , Hunter P.

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Vision image

The vision of the VPHi is to ensure that the Virtual Physiological Human is fully realised, universally adopted, and effectively used both in research and clinic.

Mission image

The VPHi acts as a catalyst to bring together a variety of different stakeholders (such as policy makers, science funding bodies, regulatory agencies, clinical organisations and industry) in order to maximise the benefit of VPH approaches for the healthcare industry and for the public good.
To achieve this goal, the VPHi will:

  • Provide a single voice for all its members
  • Ensure that VPH related research receives all over the world an adequate level of funding
  • Act as a think-tank to advise and support governmental and non-governmental institutions on research & technology development programmes and initiatives on VPH research and related topics
  • Provide a platform for the exchange of ideas, challenges, solutions and experience among the various stakeholders
  • Sustain the dissemination of VPH research, through the organisation of a number of activities, such the bi-annual VPH Conference, the VPH Summer School, on line webinars, and the VPH newsletter